摘要：For pharmacological evaluation, 3-hydroxy-N-methyl-"C"-normorphina, 3-hydroxy-N-methyl-"C"-normorphinan, and 3-hydroxy-N-methyl-"C"-homomorphinan were prepared after the Henecka's method. The former two compounds are devoid of analgesic activity, whereas the latter manifests a strong physiological activity comparable with morphine, but was found to be about three times as toxic as the natural base.
