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  • 标题:Reaction of 2, 4-Lutidine 1-Oxide and 2, 4-Dimethylquinoline 1-Oxide with Acetic Anhydride
  • 本地全文:下载
  • 作者:Sunao Furukawa
  • 期刊名称:Chemical and Pharmaceutical Bulletin
  • 印刷版ISSN:0009-2363
  • 电子版ISSN:1347-5223
  • 出版年度:1955
  • 卷号:3
  • 期号:6
  • 页码:413-416
  • DOI:10.1248/cpb1953.3.413
  • 出版社:The Pharmaceutical Society of Japan
  • 摘要:2, 4-Lutidine 1-oxide was converted to 2-hydroxymethyl-4-methylpyridine and 2-methyl-4-hydroxymethylpyridine by reaction with acetic ahydride, and its formation ratio was about 5 : 1. Besides these, 3-hydroxy-2, 4-lutidine was obtained as a phenolic base. In the case of the reaction of 2, 4-dimethylquinoline 1-oxide with acetic anhydride, 2-hydroxymethyllepidine and a small amount of 3-hydroxy-2, 4-dimethylquinoline were obtained but not 4-hydroxymethylquinaldine.
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