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  • 标题:Studies on the Syntheses of Isoquinoline Derivatives and their Analogs. XXXVI. Deamination of 2'-(p-Aminophenyl) pyrimidinosioquinoline Derivatives
  • 本地全文:下载
  • 作者:Tetsuji Kametani ; Toyoyuki Katagi
  • 期刊名称:Chemical and Pharmaceutical Bulletin
  • 印刷版ISSN:0009-2363
  • 电子版ISSN:1347-5223
  • 出版年度:1955
  • 卷号:3
  • 期号:4
  • 页码:259-262
  • DOI:10.1248/cpb1953.3.259
  • 出版社:The Pharmaceutical Society of Japan
  • 摘要:In order to establish the structure of 2'-(p-aminophenyl)-pyrimidinoisoquinoline derivative, a deaminated substance from a higher melting point was obtained from [2'-(p-aminophenyl)-4', 5'-dihydropyrimidino]-1', 6' : 1, 2-(3, 4-dihydro-6, 7-dimethoxyisoquinolinium chloride). The former was found to be identical with the product obtained by cyclization of N-(p-nitrobenzoyl-β-alanyl)-β-veratrylethylamine of higher melting point. Moreover, the hydrogenated prouct of pyrimidine moiety of pyrimidinoisoquinoline derivative was synthesized and successfully deaminated.
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