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  • 标题:Studies on Cancerocidal Substances. XVII. Reaction of Nitrogen Mustard N-Oxides and Amino Acid.
  • 本地全文:下载
  • 作者:Morizo Ishidate ; Yoshio Sakurai ; Kozo Maruyama
  • 期刊名称:Chemical and Pharmaceutical Bulletin
  • 印刷版ISSN:0009-2363
  • 电子版ISSN:1347-5223
  • 出版年度:1957
  • 卷号:5
  • 期号:5
  • 页码:435-439
  • DOI:10.1248/cpb1953.5.435
  • 出版社:The Pharmaceutical Society of Japan
  • 摘要:Rates of alkylation, oxidation, and esterification of N-methyl-bis (2-chloroethyl) amine N-oxide (HN2-O) on amino and carboxyl groups of L-alanine in a hydrogen carbonate buffer solution were discussed. The data were compared with those of the related compounds and the results suggested that the fate and reaction of HN2-O in vivo might be somewhat different from those of HN2.
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