文章基本信息

标题：Synthesis of Ureido [14C] succinic Acid and Orotic [2-14C] Acid from Urea [14C].
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作者：Shigeyuki Takeyama ; Teruhisa Noguchi ; Yoshiaki Miura 等
期刊名称：Chemical and Pharmaceutical Bulletin
印刷版ISSN：0009-2363
电子版ISSN：1347-5223
出版年度：1956
卷号：4
期号：6
页码：492-494
DOI：10.1248/cpb1953.4.492
出版社：The Pharmaceutical Society of Japan
摘要：Ureido [¹⁴C] succinic acid and orotic [2-¹⁴C] acid, which are metabolic intermediates for nucleic acid pyrimidines, were synthesized by an improved method of Nyc and Mitchell starting with aspartic acid and urea [¹⁴C], which is more easily available than potassium cyanate [¹⁴C]. The yield of orotic [2-¹⁴C] acid was 15.7% based on urea [¹⁴C].