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  • 标题:抗酸化剤に関する研究(第7報)ラットおよび家兎におけるブチルヒドロキシアニソール(BHA)酸化成績体の形成
  • 本地全文:下载
  • 作者:呉地 傳夫 ; 千田 浩子
  • 期刊名称:Journal of Health Science
  • 印刷版ISSN:1344-9702
  • 电子版ISSN:1347-5207
  • 出版年度:1977
  • 卷号:23
  • 期号:5
  • 页码:273-276
  • DOI:10.1248/jhs1956.23.273
  • 出版社:The Pharmaceutical Society of Japan
  • 摘要:Experiments were carried out to find possible in vivo formation of the oxidation products from butyl hydroxyanisole (BHA), which were confirmed to be formed by light irradiation of BHA. Diphenyl compound, essentially the same as those found in the air, were recovered from the urine of rabbits and rats treated with BHA. In studies on metabolization of these oxidation products, unchanged 2-BHA was detected in the urine. It was thereby confirmed that the reversible reaction of BHA to the diphenyl compound, and vice versa, actually occur in vivo.
  • 关键词:fate;metabolism;glucuronides;free phenol;urine;faces;butyl hydroxyanisole;rat;rabbit
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