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  • 标题:Sulfur-containing Pyridine Derivatives. XLVI. Synthesis of 7-Bromopyrido [3, 4-d] thiazoles
  • 本地全文:下载
  • 作者:Torizo Takahashi ; Osamu Yamashita
  • 期刊名称:Chemical and Pharmaceutical Bulletin
  • 印刷版ISSN:0009-2363
  • 电子版ISSN:1347-5223
  • 出版年度:1956
  • 卷号:4
  • 期号:1
  • 页码:20-24
  • DOI:10.1248/cpb1953.4.20
  • 出版社:The Pharmaceutical Society of Japan
  • 摘要:1) 3-Nitro-4-chloro-5-bromopyridine (I) reacted with KSCN in glacial acetic acid to give 3-nitro-4-amino-5-bromopyridine, and 3-nitro-4-mercapto-5-bromopyridine was obtained by the reacion of (I) and KSH in methanol. 2) 7-Bromopyrido [3, 4-d] thiazole derivatives were synthesized from 3-nitro-4-mercapto-5-bromopyridine through reduction followed by cyclization.
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