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  • 标题:Biochemical Studies on Acidomycin. IV. Avidin-combinability of Acidomycin and Its Related Compounds
  • 本地全文:下载
  • 作者:Minoru Kawashima ; Akira Miyake ; Teruji Hemmi
  • 期刊名称:Chemical and Pharmaceutical Bulletin
  • 印刷版ISSN:0009-2363
  • 电子版ISSN:1347-5223
  • 出版年度:1956
  • 卷号:4
  • 期号:1
  • 页码:56-59
  • DOI:10.1248/cpb1953.4.56
  • 出版社:The Pharmaceutical Society of Japan
  • 摘要:The action of acidomycin and its analogs on avidin, as the experimental model of the biotin-protein complex, during the formation of avidin-biotin complex (A.B-complex) was examined in vitro. It was found that these compounds failed to free biotin estimated by L.arabinosus method against inactivation by avidin. It was concluded that A.B-complex cannot be employed as a model of experiment designed to obtain some answers for the increasing urinary biotin excretion in acidomycin-injected rabbits.
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