摘要:A comparison of two extraction methods (Sep-Pak and blue rayon) of mutagens in the urine was demonstrated using the salmonella mutagenicity test. Most of the urine extracts with Sep-Pak tC18 were more mutagenic than those with blue rayon. It was suggested that the Sep-Pak extraction method was useful for the evaluation of human exposure to carcinogens/mutagens in daily life based on the mutagenic activity of the urine.
关键词:urine mutagen;extraction method;Sep-Pak cartridge;blue rayon