摘要：Recently, free radical involving active oygen speceies and nitric oxide are widely investigated because of their role in physiological, pathological and toxicological phenomena. Electron spin resonance (ESR) spectrometer is used for detecting free radicals. More recently, in vivo ESR has been developed to analyse free radical reactions in living animals. In the present paper, ESR measurement of bioradicals is reviewed, including its principle, application of spin trapping technique, in vivo ESR system, and non-invasive analysis of free radical reaction in mice.
