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  • 标题:家庭用品による接触皮膚炎の原因化学物質の追求(第7報)市販の粘着テープ類, 靴及びゴム, 皮革用接着剤中のp-tert-Butylphenol Formaldehyde Resin
  • 本地全文:下载
  • 作者:鹿庭 正昭 ; 五十嵐 良明 ; 小嶋 茂雄
  • 期刊名称:Journal of Health Science
  • 印刷版ISSN:1344-9702
  • 电子版ISSN:1347-5207
  • 出版年度:1991
  • 卷号:37
  • 期号:1
  • 页码:58-67
  • DOI:10.1248/jhs1956.37.58
  • 出版社:The Pharmaceutical Society of Japan
  • 摘要:Several cases of the patients with allergic contact dermatitis caused by an athletic tape and sneakers were reported. In patch testing p-tert-butylphenol formaldehyde resin (PTBP-FR) was found to be reactive to these patients. Therefore, analytical procedures including gas chromatography (GC), GC-mass spectrometry (GC-MS) and high performance liquid chromatography (HPLC) were developed to determine PTBP-FR and p-tert-butlyphenol (PTBP), which is a material for the synthesis of PTBP-FR, in such commercially available household products as adhesive tapes, shoes and adhesives for rubber and leather. PTBP and PTBP-FR were detected in both of the causative athletic tape and adhesive spread onto the inner lining of the sneakers. However, neither of 16 other brands of adhesive tapes nor 8 brands of the inner cushions of shoes contained PTBP and PTBP-FR. On the other hand, 7 out of 8 brands of adhesives for rubber and leather contained 0.005-0.242% of PTBP and 0.104-1.67% of PTBP-FR. From these results, it was concluded that PTBP-FR should be a causative chemical in both cases of contact dermatitis, and PTBP-FR should be given much attention as a candidate of causative chemicals in contact dermatitis from rubber and leather products.
  • 关键词:allergic contact dermatitis;athletic tape;sneaker;rubber adhesive;leather adhesive;patch testing;positive reaction;chemical analysis;determination;causative chemical;p-tert-butylphenol formaldehyde resin
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