摘要：The components of biphenyl induced urinary bladder calculus in the male rats were studied using HPLC coupled with mass spectrometry/mass spectrometry (LC-MS/MS), IR and inductive coupled plasma (ICP). Two peaks in the calculus components were detected by HPLC and LC-MS/MS. The peaks were identified as 4-hydroxybiphenyl sulfate (4-HBPSC) and 4, 4'-dihydroxybiphenyl sulfate (4, 4'-DHBPSC). 4-HBPSC was accounted for 54.6% and 4, 4'-DHBPSC was accounted for 1.5% by LC-MS/MS. 4-HBPSC was main component by these results and IR. Inorganic elements of urinary bladder calculus were accounted for 25% by ICP.
