标题：Microbial Degradation of Disinfectants. Structures of Chlorhexidine Degradation Intermediates, CHDI-B, CHDI-BR and CHDI-D, Produced by Pseudomonas Sp. Strain No. A-3
摘要：Three chlorhexidine degradation intermediates, named CHDI-B, CHDI-BR and CHDI-D, were purified from the incubation mixture for chlorhexidine degradation by Pseudomonas sp. strain No. A-3. The structures of these compounds were determined by spectroscopic analyses of 1H-NMR, 13 C-NMR and mass spectroscopy. CHDI-B has a structure in which 1 mol of 1-carboxyethyl is substituted at imine in the guanidyl group adjacent to the hexane moiety in chlorhexidine. CHDI-BR has a structure in which the carboxylic-OH in the 1-carboxyethyl moiety in CHDI-B condensed with imine in the adjacent guanidyl group to form a ring. CHDI-D has a structure in which 2 mol of 1-carboxyethyl are substituted at two imine in guanidyl groups adjacent to the hexane moiety in chlorhexidine.
