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  • 标题:競技スポーツにおけるドーピングとその検査手法
  • 本地全文:下载
  • 作者:植木 眞琴
  • 期刊名称:Journal of Health Science
  • 印刷版ISSN:1344-9702
  • 电子版ISSN:1347-5207
  • 出版年度:1998
  • 卷号:44
  • 期号:2
  • 页码:75-82
  • DOI:10.1248/jhs1956.44.75
  • 出版社:The Pharmaceutical Society of Japan
  • 摘要:The latest statistics on the drug abuse show the rapid increase of the cases by methamphetamine among adolescent boys and girls according to the official report by National Police Agency and newspapers. On the other hand, androgenic anabolic steroids (AAS) are the most notorious dope agent abused by sportsmen. Doping cases by world class Japanese athletes involved a disqualification due to steroid doping. One possible reason for such a trend is the development of trafficking route through the illegal immigrants or private import of the steroid products via Internet. Non medical use of steroid hormones in society is an escalating problem in some countries. Further more, several steroid hormones and its precursors, e. g. pregnenolone and dehydroepiandrosterone, are widely sold on the U. S. market as memory enhancing or anti-aging dietary supplements. Therefore, the introduction of the strategy against steroid doping in sports seems to be useful to reduce the approaching steroid problem in Japan to a minimum. The current testing procedure for hormone doping involve the high sensitive detection of trace amount of AAS by high resolution GC-MS after extraction using an immuno-affinity column, and the direct detection of exogenously administered natural steroids by measuring the carbon isotope ratio of the steroid skeleton. This paper refers to the recent advances in dope analysis in sports. The results obtained through the tests will also be briefly discussed.
  • 关键词:carbon isotope ratio;DHEA;carphedon;anabolic steroid;testosterone;hormone doping
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