摘要：n-Hexane was injected s.c. into normal mice to examine its influences on metallothionein concentration, and the following results were obtained. 1. The metallothionein concentration in the mouse pancreas decreased dose-dependently after the injection of n-hexane. 2. Metallothionein-bound zinc in the pancreas decreased to 51% after the injection of n-hexane and a decrease of metallothionein-bound zinc was more than that of metallothionein-unbound zinc. 3. The concentration of zinc-induced metallothionein in the mouse pancreas decreased by the simultaneous injection of n-hexane, and cadmium-induced metallothionein also decreased by the preinjection of n-hexane. These results indicate that the metallothionein concentration in the normal mouse pancreas decreased by the injection of n-hexane.
