摘要：In the influenza epidemics occurring in Osaka City during the 14 years between the 1981/82 and the 1994/95 seasons, 616 influenza virus strains of types AH1, AH3 and B were isolated from throat swabs or mouth washings of patients with influenza symptoms. Two hundred thirty strains of influenza virus were subjected to a hemagglutination test against guinea pig, goose and chick erythrocytes. Three strains (27%) of the 11 influenza AH1 viruses isolated in the 1988/89 season, 23 strains (40%) of the 58 AH3 viruses of the 1992/93 season and all 88 AH3 viruses of the 1993/94 and 1994/95 seasons failed to agglutinate chick erythrocytes despite a massive cytopathic effect on MDCK cells. However, all B viruses agglutinated chick erythrocytes. The A/Osaka City (OC)/1/89(H1) and A/OC/8/93 (H3) strains, which did not agglutinate chick erythrocytes, did not acquire agglutination reactivity to chick erythrocytes even after 7-10 passages in MDCK cells. The chick erythrocyte agglutination reactivity status of the various strains did not correlate with their antigenic differences, but did correlate with their ability to breed in MDCK cells.
