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  • 标题:Lactase non-persistence as a determinant of milk avoidance and calcium intake in children and adolescents
  • 作者:Almon Ricardo ; Sjöström Michael ; Nilsson Torbjörn K.
  • 期刊名称:Journal of Nutritional Science
  • 印刷版ISSN:2048-6790
  • 电子版ISSN:2048-6790
  • 出版年度:2013
  • 卷号:2
  • DOI:10.1017/jns.2013.11
  • 出版社:Cambridge University Press
  • 摘要:This study examines if lactase non-persistent (LNP) children and adolescents differ from those who are lactase persistent (LP) as regards milk avoidance and Ca intake. We also studied potential differences in anthropometric features related to obesity, and examined if milk avoidance is associated with lactase-persistence status. Additionally, we aimed to determine if heterozygous subjects showed an intermediary phenotype as regards Ca intake. Furthermore, we tested if LP and LNP influence vitamin D intake. The European Youth Heart Study is an ongoing international, multi-centre cohort study primarily designed to address CVD risk factors. Children (n 298, mean age 9·6 years) and adolescents (n 386, mean age 15·6 years) belonging to the Swedish part of the European Youth Heart Study were genotyped for the LCT-13910 C > T polymorphism. Mendelian randomisation was used. Milk avoidance was significantly more common in LNP adolescents (OR 3·2; 95% CI 1·5, 7·3). LP subjects had higher milk consumption (P P P
  • 关键词:Dairy products; Calcium; Vitamin D; T polymorphism; Mendelian randomisation; Milk avoidance; Nutrigenetics; Abbreviations LNP lactase non-persistence LP lactase persistence
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