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文章基本信息

  • 标题:Myelin Water Fraction MRI in a Case of Clinically Probable Amyotrophic Lateral Sclerosis
  • 作者:Yang, Jiwon ; Lee, Jongho ; Kim, EungYeop
  • 期刊名称:Korean Journal of Clinical Neurophysiology
  • 印刷版ISSN:1229-6414
  • 出版年度:2016
  • 卷号:18
  • 期号:1
  • 页码:18-20
  • DOI:10.14253/kjcn.2016.18.1.18
  • 语种:English
  • 出版社:KoreaMed Synapse
  • 摘要:

    Amyotrophic lateral sclerosis (ALS) is a progressive motor neuron degenerative disease that clinically manifests both upper and lower motor neuron signs. However, it is unknown where and how the motor neuron degeneration begins, and conflicting hypotheses have been suggested. Recent advanced radiological techniques enable us to look into ALS neuropathology in vivo. Herein, we report a case with upper motor neuron-predominant ALS in whom the results of brain magnetic resonance imaging (MRI) and myelin water fraction MRI suggest axonal degeneration.

  • 关键词:Amyotrophic Lateral Sclerosis; Magnetic Resonance imaging; Pathology
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