摘要：Background: Control of blood sugar, hypertension, and dyslipidemia are key factors in diabetesmanagement. Cucurbita ficifolia (pumpkin) is a vegetable which has been used traditionally as a remedyfor diabetes in Iran. In addition, consumption of probiotics may have beneficial effects on people withType 2 diabetes. The aim of this study was an investigation of the effects of C. ficifolia and probioticyogurt consumption alone or at the same time on blood glucose and serum lipids in diabetic patients. Methods: Eighty eligible participants randomly were assigned to four groups: 1 ? green C. ficifolia (100 g); 2 ? probiotic yogurt (150 g); 3 ? C. ficifolia plus probiotic yogurt (100 g C. ficifolia plus 150 g yogurt); and 4 ?control (dietary advice) for 8 weeks. Blood pressure, glycemic response, lipid profile, andhigh?sensitive C?reactive protein (hsCRP) were measured before and after the intervention. Results: Total cholesterol (TC) decreased significantly in yogurt and yogurt plus C. ficifoliagroups (within groups P=0.010, and P All variables changed between groups significantly except LDL?C level. Conclusions: Variables including TG, HDL?C, TC, fasting blood sugar, HbA1c, SBP, DBP, and hsCRP changed beneficially between groups. It seems that consumption of C. ficifolia andprobiotic yogurt may help treatment of diabetic patients.
