摘要：Background: Various epidemiological studies have shown that exposure to environmental pollutantsincluding polycyclic aromatic hydrocarbons (PAHs) might increase the risk of cardiovasculardiseases (CVDs) and their risk factors. This study aims to systematically review the association ofPAH exposure with metabolic impairment. Methods: Data were collected by searching for relevantstudies in international databases using the following keyword “polycyclic aromatic hydrocarbon”+“cardiovascular disease, ” PAH+CVD, polycyclic aromatic hydrocarbon and “air pollutant”+“CVD, ” and the desired data were extracted and included in the study according to the systematicreview process. Results: From the 14 articles included in the present systematic review, eight articleswere conducted on the relationship between PAH and CVDs, four articles were conducted to examinethe association of PAH exposure with blood pressure (BP), and two articles investigated the linkbetween PAH and obesity. Conclusions: Most studies included in this systematic review reporteda significant positive association of PAH exposure with increased risk of CVDs and its major riskfactors including elevated BP and obesity. These findings should be confirmed by longitudinal studieswith long?term follow?up.
