摘要:Malignant skin lesions can be widely categorized as melanoma and non-melanoma skin cancer. Skin cancer represents approximately two to four percent of all cancers in Asians. One in every three cancers diagnosed is a skin cancer and one in every five Americans will develop skin cancer in their lifetime. Objective: To determine the frequency and pattern of different malignant skin lesions in our situation. Methods: It was a prospective cross sectional study that was conducted in Surgery, Dermatology, Oncology & Plastic Surgery department of KYAMCH, Sirajgonj from January 2015 to June 2015. Total 60 patients were selected by purposive sampling as a diagnosed case of malignant skin lesion. The data were collected by the active participation of the patients' interviewed by the preformed proforma of data collection sheet and then data were gathered, decorated, tabulated after data cleaning and edition. Then the results were found and they were tested by chi-square test (qualitative data) to see their level of significance i,e p-value which was set as the cut off level at 0.05 the results are not significant. Results: The data analysis of 60 patients yielded the following results. Malignant skin lesions were commonly found in the elderly age group (>60yrs) 38.33%. Majority of them had non-melanocytic cancer (56.67%). Mean age of the male respondent was 58.79±6.54 and female respondent was 55.20 6.29 years. Maximum patients were male 66.67%. The male to female ratio was 2:1. According to anatomical site head-neck (52.94%) is the commonest site for non-melanocytic carcinoma whereas lower limb is the commonest site for malignant melanoma (69.23%). Conclusion: Malignant skin lesions were commonly present as melanoma and non-melanocytic carcinoma where man were more affected due to sunlight exposure and non-melanocytic lesions were more than malignant melanoma. Elderly age group are commonly affected. Head-neck is the commonest site for non-melanocytic lesions and lower limb is the commonest site for malignant melanoma. All cases seek initial medical attention commonly in advanced stage. KYAMC Journal Vol. 7, No.-1, Jul 2016, Page 700-706