文章基本信息

标题：ACAT1 gene ablation increases 24(S)-hydroxycholesterol content in the brain and ameliorates amyloid pathology in mice with AD
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作者：Elena Y. Bryleva ; Maximillian A. Rogers ; Catherine C.Y. Chang 等
期刊名称：Proceedings of the National Academy of Sciences
印刷版ISSN：0027-8424
电子版ISSN：1091-6490
出版年度：2010
卷号：107
期号：7
页码：3081-3086
DOI：10.1073/pnas.0913828107
语种：English
出版社：The National Academy of Sciences of the United States of America
摘要：Cholesterol metabolism has been implicated in the pathogenesis of several neurodegenerative diseases, including the abnormal accumulation of amyloid-{beta
关键词：Alzheimer disease ; cholesterol esterification ; lipid metabolism ; oxysterols