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  • 标题:Hepatocyte nuclear factor 3/fork head or "winged helix" proteins: a family of transcription factors of diverse biologic function
  • 本地全文:下载
  • 作者:E Lai ; K L Clark ; S K Burley
  • 期刊名称:Proceedings of the National Academy of Sciences
  • 印刷版ISSN:0027-8424
  • 电子版ISSN:1091-6490
  • 出版年度:1993
  • 卷号:90
  • 期号:22
  • 页码:10421-10423
  • DOI:10.1073/pnas.90.22.10421
  • 语种:English
  • 出版社:The National Academy of Sciences of the United States of America
  • 摘要:A family of transcription factors, first identified as hepatocyte nuclear factors (HNF-3 alpha, -3 beta, and -3 gamma) and as a homeotic Drosophila mutant, fork head, has been intensively studied for the past 4 years. Important findings have emerged about the structure of the DNA-binding portion of the proteins as well as biologic discoveries about the diversity of the family and its implied role in early development.
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