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  • 标题:Bioinorganic chemistry in the postgenomic era
  • 本地全文:下载
  • 作者:Ivano Bertini ; Antonio Rosato
  • 期刊名称:Proceedings of the National Academy of Sciences
  • 印刷版ISSN:0027-8424
  • 电子版ISSN:1091-6490
  • 出版年度:2003
  • 卷号:100
  • 期号:7
  • 页码:3601-3604
  • DOI:10.1073/pnas.0736657100
  • 语种:English
  • 出版社:The National Academy of Sciences of the United States of America
  • 摘要:Genome sequencing has revolutionized all fields of life sciences. Bioinorganic chemistry is certainly not immune to this influence, which is presenting unprecedented challenges. A new goal for bioinorganic chemistry is the investigation of the linkages between inorganic elements and genomic information. This requires new advancements and/or the development of new expertise in fields such as bioinformatics and genetics but also provides a driving force to push forward the exploitation of traditional analytical techniques and spectroscopic tools. The "case study" of metal homeostasis in cells is discussed to provide a flavor of the current evolution of the field.
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