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  • 标题:Structural basis of transcription: α-Amanitin–RNA polymerase II cocrystal at 2.8 Å resolution
  • 本地全文:下载
  • 作者:David A. Bushnell ; Patrick Cramer ; Roger D. Kornberg
  • 期刊名称:Proceedings of the National Academy of Sciences
  • 印刷版ISSN:0027-8424
  • 电子版ISSN:1091-6490
  • 出版年度:2002
  • 卷号:99
  • 期号:3
  • 页码:1218-1222
  • DOI:10.1073/pnas.251664698
  • 语种:English
  • 出版社:The National Academy of Sciences of the United States of America
  • 摘要:The structure of RNA polymerase II in a complex with the inhibitor -amanitin has been determined by x-ray crystallography. The structure of the complex indicates the likely basis of inhibition and gives unexpected insight into the transcription mechanism.
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