期刊名称:Proceedings of the National Academy of Sciences
印刷版ISSN:0027-8424
电子版ISSN:1091-6490
出版年度:2002
卷号:99
期号:3
页码:1218-1222
DOI:10.1073/pnas.251664698
语种:English
出版社:The National Academy of Sciences of the United States of America
摘要:The structure of RNA polymerase II in a complex with the inhibitor -amanitin has been determined by x-ray crystallography. The structure of the complex indicates the likely basis of inhibition and gives unexpected insight into the transcription mechanism.