期刊名称:Proceedings of the National Academy of Sciences
印刷版ISSN:0027-8424
电子版ISSN:1091-6490
出版年度:2003
卷号:100
期号:17
页码:9861-9866
DOI:10.1073/pnas.1633363100
语种:English
出版社:The National Academy of Sciences of the United States of America
摘要:B cell antigen receptors (BCRs) are multimeric transmembrane protein complexes comprising membrane-bound immunoglobulins (mIgs) and Ig-/Ig-{beta} heterodimers. In most cases, transport of mIgs from the endoplasmic reticulum (ER) to the cell surface requires assembly with the Ig-/Ig-{beta} subunits. In addition to Ig-/Ig-{beta