期刊名称：Proceedings of the National Academy of Sciences
印刷版ISSN：0027-8424
电子版ISSN：1091-6490
出版年度：2004
卷号：101
期号：10
页码：3686-3690
DOI：10.1073/pnas.0400072101
语种：English
出版社：The National Academy of Sciences of the United States of America
摘要：An endocrine-disrupting chemical, diethylstilbestrol (DES), a nonsteroidal estrogen, triggers oocyte maturation in fish. The morphology (the time course of the change in germinal vesicle breakdown) and an intracellular molecular event (the de novo synthesis of cyclin B) induced by DES were indistinguishable from those induced by a natural maturation-inducing hormone, 17{alpha
关键词：maturation-inducing hormone ; endocrine-disrupting chemical ; goldfish ; zebrafish
