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  • 标题:Enantioselective organocatalytic construction of pyrroloindolines by a cascade addition–cyclization strategy: Synthesis of (–)-flustramine B
  • 本地全文:下载
  • 作者:Joel F. Austin ; Sung-Gon Kim ; Christopher J. Sinz
  • 期刊名称:Proceedings of the National Academy of Sciences
  • 印刷版ISSN:0027-8424
  • 电子版ISSN:1091-6490
  • 出版年度:2004
  • 卷号:101
  • 期号:15
  • 页码:5482-5487
  • DOI:10.1073/pnas.0308177101
  • 语种:English
  • 出版社:The National Academy of Sciences of the United States of America
  • 摘要:Pyrroloindoline and bispyrroloindoline are a subclass of alkaloid structural motifs that commonly exhibit biological activity. An enantioselective organocatalytic approach to the synthesis of pyrroloindoline architecture is described. The addition-cyclization of tryptamines with {alpha
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