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  • 标题:Phospholipases C and A2 control lysosome-mediated IL-1β secretion: Implications for inflammatory processes
  • 本地全文:下载
  • 作者:Cristina Andrei ; Paola Margiocco ; Alessandro Poggi
  • 期刊名称:Proceedings of the National Academy of Sciences
  • 印刷版ISSN:0027-8424
  • 电子版ISSN:1091-6490
  • 出版年度:2004
  • 卷号:101
  • 期号:26
  • 页码:9745-9750
  • DOI:10.1073/pnas.0308558101
  • 语种:English
  • 出版社:The National Academy of Sciences of the United States of America
  • 摘要:Blocking the activity of IL-1{beta} has entered the clinical arena of treating autoimmune diseases. However, a successful outcome of this approach requires a clear definition of the mechanisms controlling IL-1{beta} release. These are still unclear as IL-1{beta
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