期刊名称:Proceedings of the National Academy of Sciences
印刷版ISSN:0027-8424
电子版ISSN:1091-6490
出版年度:2004
卷号:101
期号:26
页码:9745-9750
DOI:10.1073/pnas.0308558101
语种:English
出版社:The National Academy of Sciences of the United States of America
摘要:Blocking the activity of IL-1{beta} has entered the clinical arena of treating autoimmune diseases. However, a successful outcome of this approach requires a clear definition of the mechanisms controlling IL-1{beta} release. These are still unclear as IL-1{beta