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  • 标题:Herpes simplex virus type-1 induces IFN-α production via Toll-like receptor 9-dependent and -independent pathways
  • 本地全文:下载
  • 作者:Hubertus Hochrein ; Beatrix Schlatter ; Meredith O'Keeffe
  • 期刊名称:Proceedings of the National Academy of Sciences
  • 印刷版ISSN:0027-8424
  • 电子版ISSN:1091-6490
  • 出版年度:2004
  • 卷号:101
  • 期号:31
  • 页码:11416-11421
  • DOI:10.1073/pnas.0403555101
  • 语种:English
  • 出版社:The National Academy of Sciences of the United States of America
  • 摘要:Type I IFN production in response to the DNA virus herpes simplex virus type-1 (HSV-1) is essential in controlling viral replication. We investigated whether plasmacytoid dendritic cells (pDC) were the major tissue source of IFN-{alpha
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