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  • 标题:Oligomeric catechins: An enabling synthetic strategy by orthogonal activation and C(8) protection
  • 本地全文:下载
  • 作者:Ken Ohmori ; Naoko Ushimaru ; Keisuke Suzuki
  • 期刊名称:Proceedings of the National Academy of Sciences
  • 印刷版ISSN:0027-8424
  • 电子版ISSN:1091-6490
  • 出版年度:2004
  • 卷号:101
  • 期号:33
  • 页码:12002-12007
  • DOI:10.1073/pnas.0401651101
  • 语种:English
  • 出版社:The National Academy of Sciences of the United States of America
  • 摘要:Controlled formation of oligomeric catechins has become possible by an orthogonal synthetic strategy. Bromo-capping of the C(8) position of the flavan skeleton enabled the equimolar coupling of electrophilic and nucleophilic catechin derivatives, enabling an efficient synthetic strategy to complex catechin oligomers.
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