期刊名称：Proceedings of the National Academy of Sciences
印刷版ISSN：0027-8424
电子版ISSN：1091-6490
出版年度：1974
卷号：71
期号：10
页码：4217-4220
DOI：10.1073/pnas.71.10.4217
语种：English
出版社：The National Academy of Sciences of the United States of America
摘要：An analysis is made of various predictive methods used to locate [α]-helices and {beta}-sheets in proteins. The analysis is based on attempts to locate the [α]-helices and {beta}-sheets in adenylate kinase (ATP:AMP phosphotransferase EC 2.7.4.3 ) from the sequence without prior knowledge of the x-ray findings. Specification of the {beta}-sheet breaking and [α]-helix breaking tripeptides, a method independent of the others combined with the best of the other methods would substantially reduce the prediction of nonexistent {beta}-sheets and to a lesser extent would aid in locating [α]-helices.
关键词：secondary structure ; β-sheet ; protein conformation
