期刊名称：Proceedings of the National Academy of Sciences
印刷版ISSN：0027-8424
电子版ISSN：1091-6490
出版年度：1974
卷号：71
期号：4
页码：1474-1478
DOI：10.1073/pnas.71.4.1474
语种：English
出版社：The National Academy of Sciences of the United States of America
摘要：Thymin, a purified polypeptide isolated from bovine thymus, was shown to induce the expression of differentiation antigens characteristic of thymocytes [TL and Thy-1 ({theta})] when incubated in vitro with mouse bone marrow or spleen cells. This induction occurred in 5-10% of the cells from bone marrow after a 2-hr incubation with subnanogram concentrations of thymin. The induced cells expressed more TL and Thy-1 ({theta}) antigens than average normal thymocytes.
关键词：thymic hormone ; cytotoxic inhibition test ; bone marrow cells ; TL antigen ; Thy-1(θ) antigen
