期刊名称：Proceedings of the National Academy of Sciences
印刷版ISSN：0027-8424
电子版ISSN：1091-6490
出版年度：1974
卷号：71
期号：4
页码：1451-1455
DOI：10.1073/pnas.71.4.1451
语种：English
出版社：The National Academy of Sciences of the United States of America
摘要：Parts of two phage-coded head proteins, pE and pC, become fused during bacteriophage {lambda} head assembly. pE is the main structural component of {lambda} heads and pC is a minor head protein that is not found as such in mature heads. The bond joining the two proteins appears to be covalent and is not a disulfide bond. Only a specific subset of the sequences of each protein is found in the fusion products, and these sequences are found in the products in equimolar amounts. Two nearly identical fusion products; X1 and X2, are detected; X2 is slightly smaller than X1 and appears to be a proteolytic cleavage product of X1. The fusion reaction probably takes place on a nascent head structure.
关键词：protein processing ; viral morphogenesis ; protein splicing
