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  • 标题:Immunofluorescence Evidence for the Distribution of Cyclic AMP in Cells and Cell Masses of the Cellular Slime Molds
  • 本地全文:下载
  • 作者:Pauline Pan ; J. T. Bonner ; H. J. Wedner
  • 期刊名称:Proceedings of the National Academy of Sciences
  • 印刷版ISSN:0027-8424
  • 电子版ISSN:1091-6490
  • 出版年度:1974
  • 卷号:71
  • 期号:5
  • 页码:1623-1625
  • DOI:10.1073/pnas.71.5.1623
  • 语种:English
  • 出版社:The National Academy of Sciences of the United States of America
  • 摘要:With immunofluorescent techniques it has been possible to show that bound cyclic AMP is uniformly distributed in the nucleus and cytoplasm of a number of species of cellular slime molds. One species (which does not respond to cyclic AMP as an acrasin) is an exception and has its cyclic AMP concentrated in the nucleus during the feeding and aggregation stage. In cell masses of Dictyostelium discoideum that show early signs of differentiation the anterior, prestalk cells contain more cyclic AMP than the posterior, prespore cells.
  • 关键词:histochemistry ; fluorescent antibody staining ; cyclic nucleotide localization
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