期刊名称：Proceedings of the National Academy of Sciences
印刷版ISSN：0027-8424
电子版ISSN：1091-6490
出版年度：1975
卷号：72
期号：11
页码：4640-4644
DOI：10.1073/pnas.72.11.4640
语种：English
出版社：The National Academy of Sciences of the United States of America
摘要：Chemotactic responses are mediated by modulation of the frequency of tumbling. Studies with methionine auxotrophs of wild-type Escherichia coli and four mutants which tumble continuously show that methionine or one of its metabolites is involved in the tumbling process. Following removal of methionine, the wild type and two mutants, after various periods of time, became unable to tumble. The presence of constant levels of chemical attractants considerably shortened these periods in the three strains and eliminated tumbling in another mutant. This effect of attractants considerably shortened these periods in the three strains and eliminated tumbling in another mutant. This effect of attractants implies that methionine or some derivative of methionine is also involved in transducing chemical stimuli to bacterial responses.
