期刊名称：Proceedings of the National Academy of Sciences
印刷版ISSN：0027-8424
电子版ISSN：1091-6490
出版年度：1976
卷号：73
期号：12
页码：4454-4456
DOI：10.1073/pnas.73.12.4454
语种：English
出版社：The National Academy of Sciences of the United States of America
摘要：The development of the luminescence system in Beneckea harveyi is controlled by cyclic nucleotides at the level of transcription. In the wild type, it is repressed by exogenously added guanosine 3':5'-cyclic monophosphate and this repression is overcome by the addition of adenosine 3':5'-cyclic monophosphate. These observations alone support a model in which these nucleotides act antagonistically. On the other hand, in a mutant requiring adenosine 3':5'-cyclic monophosphate for maximum luminescence, guanosine 3':5'-cyclic monophosphate stimulates the synthesis of the luminescence system at low concentrations and inhibits it at higher concentrations. These results are apparently not consistent with a model involving a simple antagonistic effect of guanosine 3':5'-cyclic monophosphate on the action of adenosine 3':5'-cyclic monophosphate.
