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  • 标题:Gene-sized DNA molecules of the Oxytricha macronucleus have the same terminal sequence
  • 本地全文:下载
  • 作者:R M Lawn
  • 期刊名称:Proceedings of the National Academy of Sciences
  • 印刷版ISSN:0027-8424
  • 电子版ISSN:1091-6490
  • 出版年度:1977
  • 卷号:74
  • 期号:10
  • 页码:4325-4328
  • DOI:10.1073/pnas.74.10.4325
  • 语种:English
  • 出版社:The National Academy of Sciences of the United States of America
  • 摘要:The DNA in the macronucleus of the ciliated protozoan Oxytricha exists as small linear molecules with a number average size of about 3000 base pairs. Most, and possibly all, of these DNA molecules contain the same inverted terminal repeat sequence of approximately 26 base pairs. In addition to its terminal location, two inverted copies of this same sequence surround single-strand interruptions within these DNA molecules. This sequence arrangement may function in the processing of these molecules from large chromosomal precursors or in the subsequent replication of these small linear DNAs during cell reproduction.
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