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  • 标题:Isolation and characterization of the opioid peptides from rat pituitary: beta-lipotropin
  • 本地全文:下载
  • 作者:M Rubinstein ; S Stein ; L D Gerber
  • 期刊名称:Proceedings of the National Academy of Sciences
  • 印刷版ISSN:0027-8424
  • 电子版ISSN:1091-6490
  • 出版年度:1977
  • 卷号:74
  • 期号:7
  • 页码:3052-3055
  • DOI:10.1073/pnas.74.7.3052
  • 语种:English
  • 出版社:The National Academy of Sciences of the United States of America
  • 摘要:Rat beta-lipotropin was isolated from 40 anterior pituitaries using high efficiency chromatography columns and sensitive fluorometric methods. The beta-lipotropin was characterized as to molecular weight, amino acid composition, and generation of opioid activity by trypsinization. Other opioid peptides, as well as a precursor to opioid peptides with a molecular weight larger than that of beta-lipotropin, were observed in this tissue.
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