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  • 标题:Cell-free synthesis and processing of the proteins of poliovirus
  • 本地全文:下载
  • 作者:D S Shih ; C T Shih ; O Kew
  • 期刊名称:Proceedings of the National Academy of Sciences
  • 印刷版ISSN:0027-8424
  • 电子版ISSN:1091-6490
  • 出版年度:1978
  • 卷号:75
  • 期号:12
  • 页码:5807-5811
  • DOI:10.1073/pnas.75.12.5807
  • 语种:English
  • 出版社:The National Academy of Sciences of the United States of America
  • 摘要:Poliovirus RNA can be translated completely and accurately in rabbit reticulocyte lysates; the nascent poly-protein is processed to give primary products 1a, X, and 1b indistinguishable from those made in poliovirus-infected HeLa cells. The capsid precursor protein 1a is processed to form the capsid proteins VP0, VP1, and VP3, while the noncapsid precursor 1b is processed to form protein 2.
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