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  • 标题:Direct determination of volume- and time-dependence of alveolar surface tension in excised lungs
  • 本地全文:下载
  • 作者:S Schürch ; J Goerke ; J A Clements
  • 期刊名称:Proceedings of the National Academy of Sciences
  • 印刷版ISSN:0027-8424
  • 电子版ISSN:1091-6490
  • 出版年度:1978
  • 卷号:75
  • 期号:7
  • 页码:3417-3421
  • DOI:10.1073/pnas.75.7.3417
  • 语种:English
  • 出版社:The National Academy of Sciences of the United States of America
  • 摘要:We measured alveolar surface tension directly by observing the spreading properties of fluid droplets placed by micropipette within individual alveoli. Alveolar surface tension in excised rat lungs at total lung capacity and 37 degrees was 29.7 +/- 1.4 mN-m-1. In lungs held at functional residual capacity, surface tension changed slowly, rising to 9 mN-m-1 at 30 min with a subsequent approximately linear rise to 16 mN-m-1 at 115 min. Thereafter it rose more rapidly (20 mN-m-1 at 140 min), suggesting that it was not asymptotically approaching an equilibrium value.
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