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  • 标题:Another approach to in vivo estimation of genetic damage in humans
  • 本地全文:下载
  • 作者:R W Pero ; F Mitelman
  • 期刊名称:Proceedings of the National Academy of Sciences
  • 印刷版ISSN:0027-8424
  • 电子版ISSN:1091-6490
  • 出版年度:1979
  • 卷号:76
  • 期号:1
  • 页码:462-463
  • DOI:10.1073/pnas.76.1.462
  • 语种:English
  • 出版社:The National Academy of Sciences of the United States of America
  • 摘要:Direct measurements of the genetic hazards to man have been determined previously by the appearance of elevated in vivo levels of chromosome aberrations. Here we report that interindividual variations in N-acetoxy-2-acetyl-aminofluorene-induced unscheduled DNA synthesis values parallel the actual in vivo levels of chromosome damage and, therefore, may be a rapid useful supplement in genetic risk assessment for humans.
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