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  • 标题:Distribution of binding sites for 125I-labeled alpha-bungarotoxin in normal and deafferented antennal lobes of Manduca sexta
  • 本地全文:下载
  • 作者:J G Hildebrand ; L M Hall ; B C Osmond
  • 期刊名称:Proceedings of the National Academy of Sciences
  • 印刷版ISSN:0027-8424
  • 电子版ISSN:1091-6490
  • 出版年度:1979
  • 卷号:76
  • 期号:1
  • 页码:499-503
  • DOI:10.1073/pnas.76.1.499
  • 语种:English
  • 出版社:The National Academy of Sciences of the United States of America
  • 摘要:125I-Labeled alpha-bungarotoxin has been used to determine the distribution of putative acetylcholine receptors in normal and chronically deafferented antennal lobes in the brain of the moth Manduca sexta. Toxin-binding sites are confined to synaptic regions in deafferented lobes. These findings suggest that receptors can develop in the insect central nervous system independently of normal synaptic influences.
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