首页    期刊浏览 2024年12月01日 星期日
登录注册

文章基本信息

  • 标题:Is trisomy cause or consequence of murine T cell leukemia development? Studies on Robertsonian translocation mice
  • 本地全文:下载
  • 作者:J Spira ; F Wiener ; S Ohno
  • 期刊名称:Proceedings of the National Academy of Sciences
  • 印刷版ISSN:0027-8424
  • 电子版ISSN:1091-6490
  • 出版年度:1979
  • 卷号:76
  • 期号:12
  • 页码:6619-6621
  • DOI:10.1073/pnas.76.12.6619
  • 语种:English
  • 出版社:The National Academy of Sciences of the United States of America
  • 摘要:Trypsin-Giemsa banding studies on T cell leukemias induced in Robertsonian translocation mice by dimethylbenz[a]anthracene and Moloney leukemia virus show a trisomy of chromosome 15 even in cases in which chromosome 15 has undergone centromeric fusion with chromosomes 1, 5, or 6. These results suggest that the duplication of gene(s) located on chromosome 15 is of critical importance for murine T cell leukemia development.
国家哲学社会科学文献中心版权所有