期刊名称：Proceedings of the National Academy of Sciences
印刷版ISSN：0027-8424
电子版ISSN：1091-6490
出版年度：1980
卷号：77
期号：10
页码：5789-5793
DOI：10.1073/pnas.77.10.5789
语种：English
出版社：The National Academy of Sciences of the United States of America
摘要：In the cytoplasm of follicular cells of female fruitflies, a messenger RNA for one of the chorion proteins accumulates prematurely (i.e, before in vivo synthesis of the protein) but is not associated with polysomes. Subsequently, this mRNA is rapidly degraded and, thus, is not stored for later use. At a later stage in choriogenesis, the same mRNA reappears, accumulates, associates with polysomes, and is translated into a chorion protein. The transient, premature accumulation of the mRNA occurs in concert with the onset of amplification of its specific gene, a finding suggestive of a functional coupling between the two events.
