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  • 标题:Repeating structure of cytoplasmic poly(A)-ribonucleoprotein
  • 本地全文:下载
  • 作者:B W Baer ; R D Kornberg
  • 期刊名称:Proceedings of the National Academy of Sciences
  • 印刷版ISSN:0027-8424
  • 电子版ISSN:1091-6490
  • 出版年度:1980
  • 卷号:77
  • 期号:4
  • 页码:1890-1892
  • DOI:10.1073/pnas.77.4.1890
  • 语种:English
  • 出版社:The National Academy of Sciences of the United States of America
  • 摘要:A repeating structure of cytoplasmic poly(A)-ribonucleoprotein is revealed by digestion with T2 RNase. A pattern of fragments that are multiples of about 27 residues is obtained. The repeating structure is readily reconstituted from purified poly(A) and cytoplasmic factors. Reconstitution is specific for poly(A), as shown by the lack of competition by poly(G), poly(C), poly(dA), and tRNA. The repeating structure is absent from the nucleus, and so appears to be formed upon transport to the cytoplasm.
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