期刊名称：Proceedings of the National Academy of Sciences
印刷版ISSN：0027-8424
电子版ISSN：1091-6490
出版年度：1980
卷号：77
期号：5
页码：2904-2908
DOI：10.1073/pnas.77.5.2904
语种：English
出版社：The National Academy of Sciences of the United States of America
摘要：Normal rabbit serum contains an IgG-like component(s) that binds spermine as well as other polyamines. This molecule(s) has the same physicochemical properties as anti-spermine antibody obtained from rabbits immunized with spermine-thyroglobulin conjugates. However, the polyamines-binding IgG-like molecule(s), unlike anti-spermine antibody, is incapable either of precipitating a spermine-bovine serum albumin complex or of binding to a spermine-Sepharose column. These results suggest the existence of a naturally occurring anti-polyamine antibody that may have defective antibody functions.
