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  • 标题:In vitro construction of a B-tropic virus by recombination: B-tropism is a cryptic phenotype of xenotropic murine retroviruses
  • 本地全文:下载
  • 作者:J W Gautsch ; J H Elder ; F C Jensen
  • 期刊名称:Proceedings of the National Academy of Sciences
  • 印刷版ISSN:0027-8424
  • 电子版ISSN:1091-6490
  • 出版年度:1980
  • 卷号:77
  • 期号:5
  • 页码:2989-2993
  • DOI:10.1073/pnas.77.5.2989
  • 语种:English
  • 出版社:The National Academy of Sciences of the United States of America
  • 摘要:A B-tropic virus was isolated in vitro from the progeny of mouse cells doubly infected with N-tropic and xenotropic murine leukemia viruses. Biological and structural evidence is presented suggesting that the phenotypically silent structural marker for B-tropism, expressed by the xenotropic virus p30, was transferred to an N-ecotropic virus via recombination, thus resulting in the expression of a B-ecotropic murine leukemia virus.
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