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  • 标题:The pitch of chromatin DNA is reflected in its nucleotide sequence
  • 本地全文:下载
  • 作者:E N Trifonov ; J L Sussman
  • 期刊名称:Proceedings of the National Academy of Sciences
  • 印刷版ISSN:0027-8424
  • 电子版ISSN:1091-6490
  • 出版年度:1980
  • 卷号:77
  • 期号:7
  • 页码:3816-3820
  • DOI:10.1073/pnas.77.7.3816
  • 语种:English
  • 出版社:The National Academy of Sciences of the United States of America
  • 摘要:A correlation analysis of chromatin DNA nucleotide sequences reveals the clear tendency of some of the dinucleotides to be repeated along the sequences with periods of 3 and about 10.5 bases. This latter period, which is equal within experimental error to recent estimates of the pitch of the DNA double helix [Wang, J. (1979) Proc. Natl. Acad. Sci. USA 76, 200-203; Trifonov, E. & Bettecken, T. (1979) Biochemistry 18, 454-456] is interpreted as a reflection of the deformational anisotropy of the DNA molecule that facilitates its smooth folding in chromatin.
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