期刊名称:Proceedings of the National Academy of Sciences
印刷版ISSN:0027-8424
电子版ISSN:1091-6490
出版年度:1980
卷号:77
期号:8
页码:5018-5020
DOI:10.1073/pnas.77.8.5018
语种:English
出版社:The National Academy of Sciences of the United States of America
摘要:Two [Met]enkephalin-containing polypeptides have been purified from extracts of bovine and adrenal chromaffin granules. One is 8000 daltons in size and contains the enkephalin sequence at the carboxy terminus. The other (14,000 daltons) has two internal enkephalin sequences and a third sequence at the carboxy terminus. All of these sequences can be released by trypsin, indicating a possible enkephalin precursor role for the polypeptides.